CovidSeniorV1, Main, Exploration, bibRecord, 000515

Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.

Identifieur interne : 000515 ( Main/Exploration ); précédent : 000514; suivant : 000516

Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.

Auteurs : Guillaume Monneret [France] ; Donatien De Marignan [France] ; Rémy Coudereau [France] ; Céline Bernet [France] ; Florence Ader [France] ; Emilie Frobert [France] ; Morgane Gossez [France] ; Sébastien Viel [France] ; Fabienne Venet [France] ; Florent Wallet [France]

Source :

Cellular & molecular immunology [ 2042-0226 ] ; 2020.

RBID : pubmed:32728202

Descripteurs français

English descriptors

KwdEn :
- Acute Kidney Injury (diagnosis), Acute Kidney Injury (pathology), Aged (MeSH), Anti-Bacterial Agents (therapeutic use), Antifungal Agents (therapeutic use), Betacoronavirus (immunology), Betacoronavirus (pathogenicity), Compassionate Use Trials (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (genetics), Coronavirus Infections (immunology), Coronavirus Infections (virology), Critical Illness (MeSH), Fatal Outcome (MeSH), Humans (MeSH), Immunologic Factors (therapeutic use), Intensive Care Units (MeSH), Interleukin-7 (therapeutic use), Lymphopenia (drug therapy), Lymphopenia (genetics), Lymphopenia (immunology), Lymphopenia (virology), Male (MeSH), Pandemics (MeSH), Pneumonia, Ventilator-Associated (diagnosis), Pneumonia, Ventilator-Associated (drug therapy), Pneumonia, Ventilator-Associated (etiology), Pneumonia, Ventilator-Associated (pathology), Pneumonia, Viral (drug therapy), Pneumonia, Viral (genetics), Pneumonia, Viral (immunology), Pneumonia, Viral (virology), Respiration, Artificial (adverse effects), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (genetics), Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (virology).
MESH :
- chemical , therapeutic use : Anti-Bacterial Agents, Antifungal Agents, Immunologic Factors, Interleukin-7.
- adverse effects : Respiration, Artificial.
- diagnosis : Acute Kidney Injury, Pneumonia, Ventilator-Associated.
- drug therapy : Coronavirus Infections, Lymphopenia, Pneumonia, Ventilator-Associated, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- etiology : Pneumonia, Ventilator-Associated.
- genetics : Coronavirus Infections, Lymphopenia, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- immunology : Betacoronavirus, Coronavirus Infections, Lymphopenia, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- pathogenicity : Betacoronavirus.
- pathology : Acute Kidney Injury, Pneumonia, Ventilator-Associated.
- virology : Coronavirus Infections, Lymphopenia, Pneumonia, Viral, Severe Acute Respiratory Syndrome.
- Aged, Compassionate Use Trials, Critical Illness, Fatal Outcome, Humans, Intensive Care Units, Male, Pandemics.

DOI: 10.1038/s41423-020-0516-6
PubMed: 32728202
PubMed Central: PMC7387803

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000933
to stream Main, to step Curation: 000933

Le document en format XML

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<author><name sortKey="Wallet, Florent" sort="Wallet, Florent" uniqKey="Wallet F" first="Florent" last="Wallet">Florent Wallet</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.</title>
<author><name sortKey="Monneret, Guillaume" sort="Monneret, Guillaume" uniqKey="Monneret G" first="Guillaume" last="Monneret">Guillaume Monneret</name>
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<author><name sortKey="De Marignan, Donatien" sort="De Marignan, Donatien" uniqKey="De Marignan D" first="Donatien" last="De Marignan">Donatien De Marignan</name>
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<author><name sortKey="Coudereau, Remy" sort="Coudereau, Remy" uniqKey="Coudereau R" first="Rémy" last="Coudereau">Rémy Coudereau</name>
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<author><name sortKey="Bernet, Celine" sort="Bernet, Celine" uniqKey="Bernet C" first="Céline" last="Bernet">Céline Bernet</name>
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<author><name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Frobert, Emilie" sort="Frobert, Emilie" uniqKey="Frobert E" first="Emilie" last="Frobert">Emilie Frobert</name>
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<country xml:lang="fr">France</country>
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<affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Department of Virology, Infective Agents Institute, North University Hospital, Lyon, France.</nlm:affiliation>
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<author><name sortKey="Gossez, Morgane" sort="Gossez, Morgane" uniqKey="Gossez M" first="Morgane" last="Gossez">Morgane Gossez</name>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Viel, Sebastien" sort="Viel, Sebastien" uniqKey="Viel S" first="Sébastien" last="Viel">Sébastien Viel</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon</wicri:regionArea>
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<affiliation wicri:level="3"><nlm:affiliation>Hospices Civils de Lyon, Lyon-Sud University Hospital, Immunology Laboratory, 69495, Pierre Bénite, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Hospices Civils de Lyon, Lyon-Sud University Hospital, Immunology Laboratory, 69495, Pierre Bénite</wicri:regionArea>
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<author><name sortKey="Venet, Fabienne" sort="Venet, Fabienne" uniqKey="Venet F" first="Fabienne" last="Venet">Fabienne Venet</name>
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</placeName>
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<author><name sortKey="Wallet, Florent" sort="Wallet, Florent" uniqKey="Wallet F" first="Florent" last="Wallet">Florent Wallet</name>
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<country xml:lang="fr">France</country>
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<series><title level="j">Cellular & molecular immunology</title>
<idno type="eISSN">2042-0226</idno>
<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Kidney Injury (diagnosis)</term>
<term>Acute Kidney Injury (pathology)</term>
<term>Aged (MeSH)</term>
<term>Anti-Bacterial Agents (therapeutic use)</term>
<term>Antifungal Agents (therapeutic use)</term>
<term>Betacoronavirus (immunology)</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>Compassionate Use Trials (MeSH)</term>
<term>Coronavirus Infections (drug therapy)</term>
<term>Coronavirus Infections (genetics)</term>
<term>Coronavirus Infections (immunology)</term>
<term>Coronavirus Infections (virology)</term>
<term>Critical Illness (MeSH)</term>
<term>Fatal Outcome (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Immunologic Factors (therapeutic use)</term>
<term>Intensive Care Units (MeSH)</term>
<term>Interleukin-7 (therapeutic use)</term>
<term>Lymphopenia (drug therapy)</term>
<term>Lymphopenia (genetics)</term>
<term>Lymphopenia (immunology)</term>
<term>Lymphopenia (virology)</term>
<term>Male (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Ventilator-Associated (diagnosis)</term>
<term>Pneumonia, Ventilator-Associated (drug therapy)</term>
<term>Pneumonia, Ventilator-Associated (etiology)</term>
<term>Pneumonia, Ventilator-Associated (pathology)</term>
<term>Pneumonia, Viral (drug therapy)</term>
<term>Pneumonia, Viral (genetics)</term>
<term>Pneumonia, Viral (immunology)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Respiration, Artificial (adverse effects)</term>
<term>Severe Acute Respiratory Syndrome (drug therapy)</term>
<term>Severe Acute Respiratory Syndrome (genetics)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Antibactériens (usage thérapeutique)</term>
<term>Antifongiques (usage thérapeutique)</term>
<term>Atteinte rénale aigüe (anatomopathologie)</term>
<term>Atteinte rénale aigüe (diagnostic)</term>
<term>Betacoronavirus (immunologie)</term>
<term>Betacoronavirus (pathogénicité)</term>
<term>Essais cliniques à usage compassionnel (MeSH)</term>
<term>Facteurs immunologiques (usage thérapeutique)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (génétique)</term>
<term>Infections à coronavirus (immunologie)</term>
<term>Infections à coronavirus (traitement médicamenteux)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Interleukine-7 (usage thérapeutique)</term>
<term>Issue fatale (MeSH)</term>
<term>Lymphopénie (génétique)</term>
<term>Lymphopénie (immunologie)</term>
<term>Lymphopénie (traitement médicamenteux)</term>
<term>Lymphopénie (virologie)</term>
<term>Maladie grave (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie infectieuse sous ventilation assistée (anatomopathologie)</term>
<term>Pneumopathie infectieuse sous ventilation assistée (diagnostic)</term>
<term>Pneumopathie infectieuse sous ventilation assistée (traitement médicamenteux)</term>
<term>Pneumopathie infectieuse sous ventilation assistée (étiologie)</term>
<term>Pneumopathie virale (génétique)</term>
<term>Pneumopathie virale (immunologie)</term>
<term>Pneumopathie virale (traitement médicamenteux)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Sujet âgé (MeSH)</term>
<term>Syndrome respiratoire aigu sévère (génétique)</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Unités de soins intensifs (MeSH)</term>
<term>Ventilation artificielle (effets indésirables)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term>
<term>Antifungal Agents</term>
<term>Immunologic Factors</term>
<term>Interleukin-7</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Respiration, Artificial</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Atteinte rénale aigüe</term>
<term>Pneumopathie infectieuse sous ventilation assistée</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Acute Kidney Injury</term>
<term>Pneumonia, Ventilator-Associated</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Atteinte rénale aigüe</term>
<term>Pneumopathie infectieuse sous ventilation assistée</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lymphopenia</term>
<term>Pneumonia, Ventilator-Associated</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Ventilation artificielle</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Pneumonia, Ventilator-Associated</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lymphopenia</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Lymphopénie</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Betacoronavirus</term>
<term>Infections à coronavirus</term>
<term>Lymphopénie</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Betacoronavirus</term>
<term>Coronavirus Infections</term>
<term>Lymphopenia</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Acute Kidney Injury</term>
<term>Pneumonia, Ventilator-Associated</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Lymphopénie</term>
<term>Pneumopathie infectieuse sous ventilation assistée</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antibactériens</term>
<term>Antifongiques</term>
<term>Facteurs immunologiques</term>
<term>Interleukine-7</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Lymphopénie</term>
<term>Pneumopathie virale</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lymphopenia</term>
<term>Pneumonia, Viral</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Pneumopathie infectieuse sous ventilation assistée</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Compassionate Use Trials</term>
<term>Critical Illness</term>
<term>Fatal Outcome</term>
<term>Humans</term>
<term>Intensive Care Units</term>
<term>Male</term>
<term>Pandemics</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Essais cliniques à usage compassionnel</term>
<term>Humains</term>
<term>Issue fatale</term>
<term>Maladie grave</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Sujet âgé</term>
<term>Unités de soins intensifs</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32728202</PMID>
<DateCompleted><Year>2020</Year>
<Month>09</Month>
<Day>15</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>10</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2042-0226</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>17</Volume>
<Issue>9</Issue>
<PubDate><Year>2020</Year>
<Month>09</Month>
</PubDate>
</JournalIssue>
<Title>Cellular & molecular immunology</Title>
<ISOAbbreviation>Cell Mol Immunol</ISOAbbreviation>
</Journal>
<ArticleTitle>Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.</ArticleTitle>
<Pagination><MedlinePgn>1001-1003</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/s41423-020-0516-6</ELocationID>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Monneret</LastName>
<ForeName>Guillaume</ForeName>
<Initials>G</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-9961-5739</Identifier>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France. guillaume.monneret@chu-lyon.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Marignan</LastName>
<ForeName>Donatien</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Lyon-Sud University Hospital, Medical Intensive Care Unit, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Coudereau</LastName>
<ForeName>Rémy</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bernet</LastName>
<ForeName>Céline</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Lyon-Sud University Hospital, Medical Intensive Care Unit, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ader</LastName>
<ForeName>Florence</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Department of infectious Diseases, North University Hospital, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Frobert</LastName>
<ForeName>Emilie</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Department of Virology, Infective Agents Institute, North University Hospital, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gossez</LastName>
<ForeName>Morgane</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Viel</LastName>
<ForeName>Sébastien</ForeName>
<Initials>S</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-5085-443X</Identifier>
<AffiliationInfo><Affiliation>International Center of Research in Infectiology (CIRI), INSERM U1111, CNRS-UMR 5308, ENS Lyon, Université Claude Bernard Lyon, Lyon University, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Lyon-Sud University Hospital, Immunology Laboratory, 69495, Pierre Bénite, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Venet</LastName>
<ForeName>Fabienne</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Immunology Laboratory, Edouard Herriot Hospital, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wallet</LastName>
<ForeName>Florent</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Lyon-Sud University Hospital, Medical Intensive Care Unit, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>07</Month>
<Day>29</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>China</Country>
<MedlineTA>Cell Mol Immunol</MedlineTA>
<NlmUniqueID>101242872</NlmUniqueID>
<ISSNLinking>1672-7681</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000935">Antifungal Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C508605">IL7 protein, human</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007155">Immunologic Factors</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015851">Interleukin-7</NameOfSubstance>
</Chemical>
</ChemicalList>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D058186" MajorTopicYN="N">Acute Kidney Injury</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000935" MajorTopicYN="N">Antifungal Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057176" MajorTopicYN="N">Compassionate Use Trials</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016638" MajorTopicYN="N">Critical Illness</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017809" MajorTopicYN="N">Fatal Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007155" MajorTopicYN="N">Immunologic Factors</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015851" MajorTopicYN="N">Interleukin-7</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008231" MajorTopicYN="N">Lymphopenia</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053717" MajorTopicYN="N">Pneumonia, Ventilator-Associated</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012121" MajorTopicYN="N">Respiration, Artificial</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>07</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>07</Month>
<Day>19</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>7</Month>
<Day>31</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>9</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>7</Month>
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<Hour>6</Hour>
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</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32728202</ArticleId>
<ArticleId IdType="doi">10.1038/s41423-020-0516-6</ArticleId>
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<affiliations><list><country><li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Rhône-Alpes</li>
</region>
<settlement><li>Lyon</li>
<li>Pierre Bénite</li>
</settlement>
</list>
<tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Monneret, Guillaume" sort="Monneret, Guillaume" uniqKey="Monneret G" first="Guillaume" last="Monneret">Guillaume Monneret</name>
</region>
<name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
<name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
<name sortKey="Bernet, Celine" sort="Bernet, Celine" uniqKey="Bernet C" first="Céline" last="Bernet">Céline Bernet</name>
<name sortKey="Coudereau, Remy" sort="Coudereau, Remy" uniqKey="Coudereau R" first="Rémy" last="Coudereau">Rémy Coudereau</name>
<name sortKey="De Marignan, Donatien" sort="De Marignan, Donatien" uniqKey="De Marignan D" first="Donatien" last="De Marignan">Donatien De Marignan</name>
<name sortKey="Frobert, Emilie" sort="Frobert, Emilie" uniqKey="Frobert E" first="Emilie" last="Frobert">Emilie Frobert</name>
<name sortKey="Frobert, Emilie" sort="Frobert, Emilie" uniqKey="Frobert E" first="Emilie" last="Frobert">Emilie Frobert</name>
<name sortKey="Gossez, Morgane" sort="Gossez, Morgane" uniqKey="Gossez M" first="Morgane" last="Gossez">Morgane Gossez</name>
<name sortKey="Venet, Fabienne" sort="Venet, Fabienne" uniqKey="Venet F" first="Fabienne" last="Venet">Fabienne Venet</name>
<name sortKey="Viel, Sebastien" sort="Viel, Sebastien" uniqKey="Viel S" first="Sébastien" last="Viel">Sébastien Viel</name>
<name sortKey="Viel, Sebastien" sort="Viel, Sebastien" uniqKey="Viel S" first="Sébastien" last="Viel">Sébastien Viel</name>
<name sortKey="Wallet, Florent" sort="Wallet, Florent" uniqKey="Wallet F" first="Florent" last="Wallet">Florent Wallet</name>
</country>
</tree>
</affiliations>
</record>

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Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.

Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient.

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